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Power outage: If the refrigerator door stays closed, the interior remains below 46°F for approximately 4 hours (per USDA food safety data, which applies equally to medication) If the outage lasts less than 4 hours and the door was not opened, the medication is safe If the outage exceeds 4 hours, check the medication's temperature with a thermometer when power returns If the medication is still cold to the touch (below 50°F), it is likely salvageable
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